metsign software Search Results


metsign software  (MathWorks Inc)
90
MathWorks Inc metsign software
An example of spectrum deconvolution by <t>MetSign.</t> (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.
Metsign Software, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/metsign software/product/MathWorks Inc
Average 90 stars, based on 1 article reviews
metsign software - by Bioz Stars, 2026-04
90/100 stars
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software matlab 2010a  (MathWorks Inc)
90
MathWorks Inc software matlab 2010a
An example of spectrum deconvolution by <t>MetSign.</t> (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.
Software Matlab 2010a, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/software matlab 2010a/product/MathWorks Inc
Average 90 stars, based on 1 article reviews
software matlab 2010a - by Bioz Stars, 2026-04
90/100 stars
  Buy from Supplier

Image Search Results


An example of spectrum deconvolution by MetSign. (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.

Journal: Analytical chemistry

Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

doi: 10.1021/ac3016856

Figure Lengend Snippet: An example of spectrum deconvolution by MetSign. (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.

Article Snippet: MetSign software was implemented using MATLAB 2010b and is free for purpose of academic research.

Techniques:

An example of peak picking by MetSgin and MZmine2.6. (A) Peak fitting results by MetSign using mixture EMG model. (B) Five peak components deconvoluted by peak detection and EMG fitting algorithm by MetSign. (C), (D) and (E) are the peak deconvolution results on same data by MZmine2.6. MetSign detected five peaks including four dominant peaks and one hidden peak; while MZmine2.6 correctly detected the two abundant peaks on the right and incorrectly considered the three peaks on the left as one peak.

Journal: Analytical chemistry

Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

doi: 10.1021/ac3016856

Figure Lengend Snippet: An example of peak picking by MetSgin and MZmine2.6. (A) Peak fitting results by MetSign using mixture EMG model. (B) Five peak components deconvoluted by peak detection and EMG fitting algorithm by MetSign. (C), (D) and (E) are the peak deconvolution results on same data by MZmine2.6. MetSign detected five peaks including four dominant peaks and one hidden peak; while MZmine2.6 correctly detected the two abundant peaks on the right and incorrectly considered the three peaks on the left as one peak.

Article Snippet: MetSign software was implemented using MATLAB 2010b and is free for purpose of academic research.

Techniques:

Comparison of alignment results among MetSign, MZmine2.6, XCMS2 with retention time correction, and XCMS2 without retention time correction. (A) εm/z ≤ 6 ppm. (B) εm/z ≤ 10 ppm. The εm/z was set as 0.025 for XCMS2 as specified by the software.

Journal: Analytical chemistry

Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

doi: 10.1021/ac3016856

Figure Lengend Snippet: Comparison of alignment results among MetSign, MZmine2.6, XCMS2 with retention time correction, and XCMS2 without retention time correction. (A) εm/z ≤ 6 ppm. (B) εm/z ≤ 10 ppm. The εm/z was set as 0.025 for XCMS2 as specified by the software.

Article Snippet: MetSign software was implemented using MATLAB 2010b and is free for purpose of academic research.

Techniques: Software